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What the San Onofre Nuclear Generating Station looks like with demolition at 80%
The San Diego Union-TribuneDec 1, 2025By Rob Nikolewski

What the San Onofre Nuclear Generating Station looks like with demolition at 80%

The first of the iconic domes that loom over Interstate 5 will start coming down in the fourth quarter of next year.

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Kansas City Weather forecast: Which areas will expect heavy snowfall and when — full timeline of Monday’s winter storm
The Times of IndiaDec 1, 2025By Aastha Raj

Kansas City Weather forecast: Which areas will expect heavy snowfall and when — full timeline of Monday’s winter storm

Kansas City Weather: Snowfall has begun across the Kansas City metropolitan area, prompting officials to declare a First Alert Weather Alert Day for Monday as conditions worsen. A Winter Weather Advisory will remain in place through Monday evening, with forec…

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Here’s everything new Apple TV has coming in December
9to5MacDec 1, 2025By Ryan Christoffel

Here’s everything new Apple TV has coming in December

Apple TV (only $5.99/month for Cyber Monday) is having its biggest year ever, and December brings its expected biggest movie yet with F1 The Movie. Other highlights for the month include new episodes of sci-fi hit Pluribus, a nature docuseries, and a brand ne…

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Freerepublic.comDec 1, 2025By Cypher News

The Frozen Dessert Scam: ‘Ice Cream’ Isn’t Actually Ice Cream Anymore

Companies didn’t improve the recipe — they cheapened it. The scam is simple: charge the same, deliver less. The label tells the truth the ad won’t. ********************************************************************* BRIEFING Grant here. Here’s a story that’…

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WHO warning over shortage of obesity jabs
BBC NewsDec 1, 2025

WHO warning over shortage of obesity jabs

Too few people who could benefit from so-called "skinny jabs" are able to access them, says WHO.

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Yahoo EntertainmentDec 1, 2025

Why Buying This Dominant Travel Disrupter Today Will Net 200% Returns

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The Asian Division’s Florence Tan Moeson Fellowship: Now Accepting Applications for 2026
Loc.govDec 1, 2025By Jonathan Loar

The Asian Division’s Florence Tan Moeson Fellowship: Now Accepting Applications for 2026

The Asian Division is now accepting applications for its Florence Tan Moeson Fellowship, which supports short-term research visits to the Asian Reading Room at the Library of Congress. This year's application deadline is before midnight (ET), Sunday, January …

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Hegseth Makes Fun of War Crimes With Twisted AI Children’s Book Meme
The New RepublicDec 1, 2025By Malcolm Ferguson

Hegseth Makes Fun of War Crimes With Twisted AI Children’s Book Meme

Defense Secretary Pete Hegseth posted an AI image of popular children’s character Franklin the Turtle extrajudicially blowing up “drug boats,” just days after it was revealed he potentially committed a war crime of his own. Hegseth’s post—another installment …

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Death of Teenager on Carnival Cruise Ship Ruled a Homicide
Insurance JournalDec 1, 2025By Admin

Death of Teenager on Carnival Cruise Ship Ruled a Homicide

The death of a Florida teenager on a Carnival cruise ship earlier this month has been ruled a homicide, the latest development in a case that has drawn international attention and sparked intense speculation on social media. Anna Kepner’s cause …

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He once cleaned tables, washroom for Rs 20 an hour. Then left a Rs 1 crore job. Today, his 4-year-old company is worth Rs 325 crore
The Times of IndiaDec 1, 2025By ET Online

He once cleaned tables, washroom for Rs 20 an hour. Then left a Rs 1 crore job. Today, his 4-year-old company is worth Rs 325 crore

Nitin Kalra's journey from cleaning tables for ₹20 an hour to building a ₹325 crore company is remarkable. He spotted a gap in the healthy snack market. His daughter's health challenge inspired the brand Let's Try. An investment from Aman Gupta on Shark Tank …

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23 Best GoPro and Camera Deals for Cyber Monday (2025)
WiredDec 1, 2025By Scott Gilbertson

23 Best GoPro and Camera Deals for Cyber Monday (2025)

Score a great deal on our favorite action cameras, 360 cameras, and more with these Cyber Monday sales.

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Johannesburg’s produce market has supplied the informal sector for decades: a refresh is due
The Conversation AfricaDec 1, 2025By Marc Wegerif, Senior Lecturer, Development Studies, University of Pretoria

Johannesburg’s produce market has supplied the informal sector for decades: a refresh is due

The Johannesburg Market has many challenges, including poor governance and infrastructure decay. Its story underscores the need to protect such markets nationwide.

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I've covered Cyber Monday for 6 years — these are the 319+ absolute best deals of 2025
NBC NewsDec 1, 2025By Zoe Malin

I've covered Cyber Monday for 6 years — these are the 319+ absolute best deals of 2025

Cyber Monday deals are live and you have less than 24 hours to save on AirPods, Dyson vacuums, Medicube skin care, Uggs and more.

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OpenAGI emerges from stealth with an AI agent that it claims crushes OpenAI and Anthropic
VentureBeatDec 1, 2025By Michael Nuñez

OpenAGI emerges from stealth with an AI agent that it claims crushes OpenAI and Anthropic

MIT spinout OpenAGI claims its Lux AI agent scores 83.6% on a rigorous computer-use benchmark where OpenAI's Operator hits 61.3% — at one-tenth the cost.

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Amazon and Visa Team to Boost Agentic Commerce
pymnts.comDec 1, 2025By PYMNTS

Amazon and Visa Team to Boost Agentic Commerce

Visa and Amazon Web Services want to help developers and enterprises deploy agentic AI commerce projects. To that end, the companies announced Monday (Dec. 1) the launch of a partnership that will see Visa list its Intelligence Commerce platform in the Amazon…

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Muni Long Departs Brandy & Monica’s ‘The Boy Is Mine’ Tour Amid Health Concerns—‘It’s Not Safe For Me To Continue’
BossipDec 1, 2025By Kerbi Lynn

Muni Long Departs Brandy & Monica’s ‘The Boy Is Mine’ Tour Amid Health Concerns—‘It’s Not Safe For Me To Continue’

R&B singer Muni Long exits 'The Boy Is Mine Tour' due to lupus, prioritizing health over grueling schedule. The post Muni Long Departs Brandy & Monica’s ‘The Boy Is Mine’ Tour Amid Health Concerns—‘It’s Not Safe For Me To Continue’ appeared first on Bossip.

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Could the IBX Be Fully Automated?
Brownstoner.comDec 1, 2025By amNY

Could the IBX Be Fully Automated?

by Barbara Russo-Lennon, amNY A NYC urban planning research group published a study about train operation, calling on the MTA to make a driverless system for its planned Interborough Express (IBX) rail line through Brooklyn and Queens. As part of its study, N…

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A forgotten hotel credit on a United card saved me $200 — and it was super easy to use
The Points GuyDec 1, 2025By Summer Hull

A forgotten hotel credit on a United card saved me $200 — and it was super easy to use

Sometimes there are valuable card benefits hidden in plain sight. Here's how one I almost forgot about saved me $200 on a hotel stay.

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Top 5 Must-Watch Apple TV Shows This Week: December 1–7, 2025
Screen RantDec 1, 2025By Greg MacArthur

Top 5 Must-Watch Apple TV Shows This Week: December 1–7, 2025

These 5 must-watch new December 2025 Apple TV shows are perfect to binge-watch this week. #1 is now trending worldwide on Apple TV's global charts.

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Why being single might feel empowering as a woman in your 20s, but not your 30s
The Conversation AfricaDec 1, 2025By Alicia Denby, Lecturer in Sociology and Criminology, Manchester Metropolitan University

Why being single might feel empowering as a woman in your 20s, but not your 30s

Singlehood has been rebranded as a time for self-love, self-prioritisation and personal growth.

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(PR) GEEKOM Launches World's First All-Metal Ultralight Laptop: GeekBook X14 Pro
Techpowerup.comDec 1, 2025By T0@st

(PR) GEEKOM Launches World's First All-Metal Ultralight Laptop: GeekBook X14 Pro

GEEKOM has officially announced the upcoming launch of its GeekBook X series, scheduled for mid-December 2025. Designed to balance portability and performance, the new lineup aims to elevate productivity, creative workflows, and everyday entertainment. Leadin…

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Britain’s ponds are disappearing – here’s why restoring them is vital for wildlife and climate resilience
The Conversation AfricaDec 1, 2025By Lucy Clarke, Senior Lecturer, Department of Animal, Rural and Environmental Sciences, Nottingham Trent University

Britain’s ponds are disappearing – here’s why restoring them is vital for wildlife and climate resilience

Across Britain, ponds are quietly vanishing. Reviving them is one of the simplest ways to boost biodiversity and climate resilience.

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The Best Film Performances of 2025
VultureDec 1, 2025By Joe Reid

The Best Film Performances of 2025

The year was so competitive that Stellan Skarsgård, Emma Stone, and Paul Mescal didn’t make the cut. Here are our favorite film performances of 2025.

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Molecule Vital to Happiness Found in Material From Asteroid Bennu
ScienceAlertDec 1, 2025By Michelle Starr

Molecule Vital to Happiness Found in Material From Asteroid Bennu

A critical nutrient used to produce the neurotransmitter serotonin may have turned up in samples collected from asteroid Bennu by NASA's OSIRIS-REx mission.

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How to Survive the "Sundown Scaries" as a New Parent
POPSUGARDec 1, 2025By Taylor Andrews

How to Survive the "Sundown Scaries" as a New Parent

If you're a parent, you may already be familiar with the emotional shift that can happen when the sun goes down. During the day, you might feel OK, but at night, the waves of anxiety can roll in: "Am I a bad parent?" "Am I doing this right?" "Is there somethi…

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The Severe Ecological Ramifications of Offshore Windfarms in the Atlantic
Wattsupwiththat.comDec 1, 2025By Charles Rotter

The Severe Ecological Ramifications of Offshore Windfarms in the Atlantic

They presume that a system as complex as the Atlantic continental shelf will behave according to their intentions rather than according to its physics.

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Superpunch.netDec 1, 2025By noreply@blogger.com (John)

Gingerbread dumpster (Holiday roundup)

Thinking back to five years ago when I made a gingerbread dumpster fire for Christmas[image or embed] — Birds Are Dinosaurs = (@birdsaredinosaurs.bsky.social) November 30, 2025 at 1:55 PM i thought this was some non-sequitur, dadaist bit, but no, mil…

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Surprise: Cleantech Spending May Hit Record Despite Trump’s Carbon Push
ForbesDec 1, 2025By Alan Ohnsman, Forbes Staff, Alan Ohnsman, Forbes Staff https://www.forbes.com/sites/alanohnsman/

Surprise: Cleantech Spending May Hit Record Despite Trump’s Carbon Push

This week’s Current Climate newsletter also looks at how AI is ushering in a new nuclear age and investing in developing nations amid a pullback in U.S. aid and private funding

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5 Great Adult Swim Shows Nobody Talks About
ComicBook.comDec 1, 2025By Shawn Lealos

5 Great Adult Swim Shows Nobody Talks About

Image Courtesy of Adult Swim Adult Swim has some great shows that nobody talks about. The network launched in 2001 as a block on the Cartoon Network, and it presented animated shows that were aimed toward an adult audience. This means that the cartoons on Adu…

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Is Chula Vista’s dream of a public university finally coming into focus?
KPBSDec 1, 2025By Kori Suzuki

Is Chula Vista’s dream of a public university finally coming into focus?

After decades of planning and setbacks, South Bay officials are laying the groundwork for a multi-university campus that houses academic programs from schools across the San Diego-Tijuana metro.

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The Only Cyber Monday Deals That Matter From Apple to Amazon - Up to 80% Off
POPSUGARDec 1, 2025By Haley Lyndes

The Only Cyber Monday Deals That Matter From Apple to Amazon - Up to 80% Off

If you're thinking, "sh*t, I really should've done some Black Friday shopping," you're in luck - Cyber Monday is here for that. It's all about convenience and making up for what you missed. You might not be able to run to a store IRL, but you can still snag b…

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Avalon GloboCare Reports Q3 2025 Progress with KetoAir™, Holistic Health Initiatives, and International Expansion
GlobeNewswireDec 1, 2025By Avalon GloboCare Corp.

Avalon GloboCare Reports Q3 2025 Progress with KetoAir™, Holistic Health Initiatives, and International Expansion

FREEHOLD, N.J., Dec. 01, 2025 (GLOBE NEWSWIRE) -- Avalon GloboCare Corp. (“Avalon” or the “Company”) (NASDAQ: ALBT), a developer of precision diagnostic consumer products, today announced a series of Q3 2025 advancements for KetoAir™, including expanded deplo…

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Molecular response to the non-lytic peptide bac7 (1–35) triggers disruption of Klebsiella pneumoniae biofilm
Plos.orgDec 1, 2025By Robert L. Beckman I.V., Berta Martinez, Flor Z. Santiago, Gabriela N. Echeverria, Bruno V. Pinheiro, Marcelo D.T. Torres, Logan Suits, Shantal Garcia, Paeton L. Wantuch, Cesar de la Fuente-Nunez, Prahathees Eswara, David A. Rosen, Renee M. Fleeman

Molecular response to the non-lytic peptide bac7 (1–35) triggers disruption of Klebsiella pneumoniae biofilm

Author summary Klebsiella pneumoniae is a top-priority pathogen for new therapies, with many strains already approaching pan-drug resistant status. Biofilm formation further complicates treatment, yet biofilm-active therapeutics have not reached the clinic, i…

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Glia-to-glia serotonin signaling directs MMP-dependent infiltration for experience-dependent synapse pruning
Plos.orgDec 1, 2025By Vanessa Kay Miller, Kendal Broadie

Glia-to-glia serotonin signaling directs MMP-dependent infiltration for experience-dependent synapse pruning

A prior PLOS Biology study showed that experience-dependent synapse elimination in a Drosophila brain circuit depends on glial serotonergic signaling. This study shows that serotonin coordinates two distinct glial classes, with MMP-1 acting downstream of sero…

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Visit-to-visit glycemic variability is associated with lung function variables and lung function impairment in individuals with type 2 diabetes
Plos.orgDec 1, 2025By Yi-Hua Wu, Chia-Ing Li, Chiu-Shong Liu, Chih-Hsueh Lin, Shing-Yu Yang, Cheng-Chieh Lin, Tsai-Chung Li

Visit-to-visit glycemic variability is associated with lung function variables and lung function impairment in individuals with type 2 diabetes

Glycemic variability (GV) is an emerging biomarker of glycemic control and may be a predictor for lung function impairment in persons with type 2 diabetes mellitus (T2DM). However, the associations between GV and lung function variables and lung function impa…

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Global trends in Alzheimer’s disease and other dementias: A comprehensive analysis of incidence, socio-demographic variations, and future projections
Plos.orgDec 1, 2025By Ruixue Qin, Huijuan Zhao, Hui Gao, He Liu

Global trends in Alzheimer’s disease and other dementias: A comprehensive analysis of incidence, socio-demographic variations, and future projections

Background Alzheimer’s disease and other dementias (ADRD) are significant global health concerns, with rising incidence rates and substantial social and economic implications due to population aging. Methods We investigated trends in ADRD incidence from 199…

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The EQo-Mental project: A protocol for a mixed-methods study on occupational balance and mental health in parents of children with developmental delays
Plos.orgDec 1, 2025By Desirée Valera-Gran, Miriam Hurtado-Pomares, Iris Juárez-Leal, Rocío Muñoz-Sánchez, Irene Campos-Sánchez, Paula Noce, Jessica Piñero, Eva-María Navarrete-Muñoz

The EQo-Mental project: A protocol for a mixed-methods study on occupational balance and mental health in parents of children with developmental delays

Background Parents of children with developmental delays (DD) often face significant challenges that affect their mental health and occupational balance. While early intervention services traditionally focus on child development, the occupational needs and we…

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Mechanistic insight into the antidiabetic effects of Ficus hispida fruits: Inhibition of intestinal glucose absorption and pancreatic beta-cell apoptosis
Plos.orgDec 1, 2025By Nusaiba Jahan, Noimul Hasan Siddiquee, Rifayat Ara Khanom Riva, Nur Uddin Chowdhury, Marjanur Rahman Bhuiyan, Khondoker Shahin Ahmed, Hemayet Hossain, Sadikur Rahman Shuvo, AFM. Shahid Ud Daula

Mechanistic insight into the antidiabetic effects of Ficus hispida fruits: Inhibition of intestinal glucose absorption and pancreatic beta-cell apoptosis

The worldwide health impact of Type 2 diabetes mellitus (T2DM) is marked by the dysregulation of glucose metabolism caused by α-glucosidase-mediated carbohydrate degradation and pancreatic β-cell apoptosis through caspase-3 activation. This study aimed to tho…

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Chemosensory protein 3 is a brain host factor for the induction of enhanced-locomotory activity in the BmNPV-silkworm infection model
Plos.orgDec 1, 2025By Min Feng, Shigang Fei, Athanasios Papakyriakou, Eleanna Christodoulou, Wenxuan Lai, Wenjie Luo, Junming Xia, Yigui Huang, Spyros E. Zographos, Luc Swevers, Jingchen Sun

Chemosensory protein 3 is a brain host factor for the induction of enhanced-locomotory activity in the BmNPV-silkworm infection model

Author summary Baculoviruses, a diverse group of insect-specific DNA viruses, have long been known to induce hyperactive behavior known as enhanced locomotory activity (ELA) and tree-top disease in their lepidopteran hosts. However, our understanding of the h…

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Precarious employment and gender-based violence against migrant women: A scoping review mapping the intersections
Plos.orgDec 1, 2025By Cyndirela Chadambuka, Prossy Kiddu Namyalo, Rhea Raghunauth, Navya Arora, Fiona Kouyoumdjian, Beverley M. Essue

Precarious employment and gender-based violence against migrant women: A scoping review mapping the intersections

The risk of gender-based violence (GBV) against migrant women is largely exacerbated by precarious employment opportunities available to them as they go through the resettlement process. Despite the risk that the connection of precarious employment and GBV po…

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Treatment and prevention of HIV/AIDS: Unfinished business
Plos.orgDec 1, 2025By Anthony S. Fauci, Gregory K. Folkers

Treatment and prevention of HIV/AIDS: Unfinished business

In recognition of World AIDS Day 2025, this Perspective by Gregory Folkers and Anthony Fauci reflects on the progress made in antiretroviral treatments and prevention of HIV/AIDS, highlighting promising therapeutic developments and looking ahead to what is ne…

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Two-leaves and many bites: Profiling dog-bites and adherence to rabies prophylaxis in tea-estate communities of Udalguri District, Assam, India
Plos.orgDec 1, 2025By Harish Kumar Tiwari, Parimala Mohanty, Rasika G. Shirke, Aina Unnikrishnan Kurup, Chalasani Satwik, Shanti Priya Kindo, Riya Shigwan, Karma Wangdi, Jully Gogoi-Tiwari, Laura Cunha Silva, Salome Dürr

Two-leaves and many bites: Profiling dog-bites and adherence to rabies prophylaxis in tea-estate communities of Udalguri District, Assam, India

Author summary This retrospective study analysed secondary data of hospital and dispensary records from 11 tea estates in Assam’s Udalguri district between January 2022 and May 2024 to estimate the incidence of dog bites, profile affected individuals, and ass…

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Assessing risks of dengue, chikungunya and Zika transmission associated to Aedes albopictus in Chania, Greece, 2017–2018
Plos.orgDec 1, 2025By Sk Shahid Nadim, Francesco Menegale, Mattia Manica, Alexander R. Kaye, Georgios Balatsos, Marina Bisia, Verena Pichler, Piero Poletti, Stefano Merler, Alessandra Della Torre, Robin N. Thompson, Antonios Michaelakis, Giorgio Guzzetta

Assessing risks of dengue, chikungunya and Zika transmission associated to Aedes albopictus in Chania, Greece, 2017–2018

Author summary Aedes albopictus is a highly invasive mosquito capable of transmitting arboviruses such as dengue, chikungunya, and Zika. In this work, we leverage mosquito capture data collected over two years of entomological surveillance in Chania - a major…

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DLK orchestrates a modular transcriptional response to axon injury with separate roles for Fos and Jun
Plos.orgDec 1, 2025By Gibarni Mahata, Li Chen, Gregory O. Kothe, Melissa M. Rolls

DLK orchestrates a modular transcriptional response to axon injury with separate roles for Fos and Jun

Author summary Neuronal cells, unlike other cell types, cannot divide or be replaced after injury. Axon damage is particularly deleterious as many neurons have a single axon that is required to relay signals to target cells. Axon regeneration allows some neur…

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Loss of function of chromatin remodeler OsCLSY4 leads to RdDM-mediated mis-expression of endosperm-specific genes affecting grain qualities
Plos.orgDec 1, 2025By Avik Kumar Pal, Saumyapriya Rana, Riju Dey, Padubidri V. Shivaprasad

Loss of function of chromatin remodeler OsCLSY4 leads to RdDM-mediated mis-expression of endosperm-specific genes affecting grain qualities

Author summary The endosperm performs a unique physiological function similar to that of mammalian placenta, providing nourishment to the developing plant embryo and acting as a signaling hub. This tissue is distinct from the other plant tissues in its ploidy…

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Carolina Herrera Resort 2026: Vibrant and Strong
WWDDec 1, 2025By Emily Mercer

Carolina Herrera Resort 2026: Vibrant and Strong

Carolina Herrera Resort 2026 Ready-to-Wear Runway, Fashion Show & Collection Review: Wes Gordon looked to ancient Greece as inspiration for his colorful, sculptural yet fluid and strong resort collection.

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Tim Blake Nelson Has Been in His Fair Share of Superhero Movies. His New Novel Takes Us Behind the Scenes.
menshealth.comDec 1, 2025By Tim Blake Nelson

Tim Blake Nelson Has Been in His Fair Share of Superhero Movies. His New Novel Takes Us Behind the Scenes.

He's appeared in The Incredible Hulk, Captain America: Brave New World, and HBO's Watchmen. In an exclusive excerpt of the actor-turned-author's second novel, Superhero, he explores the inner workings of the Hollywood franchise machine.

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What Made The Early Aughts The Golden Age For Christmas Movies … And Why Did It End?
DeciderDec 1, 2025By mliss1578

What Made The Early Aughts The Golden Age For Christmas Movies … And Why Did It End?

Hallmark just doesn't hit like that Bad Santa/Elf combo.

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The 16 Rules For Dining Out Every Man Should Know
esquire.comDec 1, 2025By Mark Alan Burger

The 16 Rules For Dining Out Every Man Should Know

A back-of-the-envelope guide to impressing your date, your in-laws, your boss—anyone with whom you're sharing a table.

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Development of a low-cost culture medium from industrial and environmental by-products for sustainable cultivation of Lactic Acid Bacteria
Plos.orgDec 1, 2025By Michele Letitia Tchabou Tientcheu, Pierre Marie Kaktcham, Edith Marius Foko Kouam, Laverdure Tchamani Piame, Lysette Chabrone Djodjeu Kamega, Aarzoo, Agnihotri Shekhar, Singh Bhim Pratap, François Zambou Ngoufack

Development of a low-cost culture medium from industrial and environmental by-products for sustainable cultivation of Lactic Acid Bacteria

Conventional culture media such as de Man, Rogosa and Sharpe are essential for the growth of lactic acid bacteria and the production of metabolites used in the food and pharmaceutical industries. However, their high cost limits their application, particularly…

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Assessing the chemical profile and biological potentials of Tamarix smyrnensis flower extracts using different solvents by in vitro, in silico, and network methodologies
Plos.orgDec 1, 2025By Erdi Can Aytar, Emine Incilay Torunoğlu, Abidin Gümrükçüoğlu, Saleh Al-Farraj, Alper Durmaz, Mika Sillanpää

Assessing the chemical profile and biological potentials of Tamarix smyrnensis flower extracts using different solvents by in vitro, in silico, and network methodologies

This study evaluated the antioxidant properties, phytochemical content, and protein interactions of Tamarix smyrnensis flower extracts prepared with different solvents (methanol, ethanol, ethyl acetate). The antioxidant activities were assessed using the DPPH…

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Bimodal expression of Type 3 Secretion System 2 enables cooperative virulence among intracellular Salmonella Typhimurium
Plos.orgDec 1, 2025By Milada Pospíšilová, Alona Dreus, Paulina Matheova, Jana Schmidtova, Barbora Pravdova, Michaela Blazikova, Martin Capek, Ondrej Cerny

Bimodal expression of Type 3 Secretion System 2 enables cooperative virulence among intracellular Salmonella Typhimurium

Author summary Systemic infection and survival of Salmonella within host cells depend on expression of effector proteins that manipulate host cell functions. Here, we show that expression of these effectors varies among individual bacteria residing within the…

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Neural mechanisms of flexible perceptual inference
Plos.orgDec 1, 2025By John Schwarcz, Jan Bauer, Haneen Rajabi, Gabrielle Marmur, Robert Reiner, Eran Lottem, Jonathan Kadmon

Neural mechanisms of flexible perceptual inference

Author Summary How do animals adapt their behavior when the rules of their environment change unexpectedly? In this study, we address this fundamental question by training mice to perform a task in which they must infer not only the current state of their env…

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DDGWizard: Integration of feature calculation resources for analysis and prediction of changes in protein thermostability upon point mutations
Plos.orgDec 1, 2025By Mingkai Wang, Khaled Jumah, Qun Shao, Katarzyna Kamieniecka, Yihan Liu, Krzysztof Poterlowicz

DDGWizard: Integration of feature calculation resources for analysis and prediction of changes in protein thermostability upon point mutations

Author summary A protein’s ability to maintain its structure under high temperatures, known as thermostability, is critical for many industrial and therapeutic applications and might be affected by genetic mutations. To address the challenge, we built a robus…

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Therapeutic itineraries of children after snakebites in the Brazilian Amazon: A thematic drawing-and-story study
Plos.orgDec 1, 2025By Joseir Saturnino Cristino, Altair Seabra Farias, Erica Silva Carvalho, Jacqueline Sachett, Fan Hui Wen, Felipe Murta, Vinícius Azevedo Machado, Wuelton Monteiro

Therapeutic itineraries of children after snakebites in the Brazilian Amazon: A thematic drawing-and-story study

Author summary Snakebite envenomation represents a significant public health challenge in the Brazilian Amazon, particularly among children. Due to their smaller body size and limited access to emergency care in remote areas, children are at higher risk of co…

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Anthropophagic Florida mosquito species are poor vectors of prototype and emerging strains of oropouche virus
Plos.orgDec 1, 2025By Dongmin Kim, Tanise Moitinho S. Stenn, Shelby M. Dittman, Yesenia L. Sanchez, Charlotte A. Addae, Limarie J. Reyes Torres, Eva A. Buckner, Nathan D. Burkett-Cadena, Barry W. Alto

Anthropophagic Florida mosquito species are poor vectors of prototype and emerging strains of oropouche virus

Author summary Oropouche virus (OROV) is an emerging virus that is spreading rapidly across tropical regions of the Americas. In 2024, over 100 travel-related cases were reported in Florida, raising concerns about the potential for local transmission. In Sout…

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The Best Movies of 2025
VultureDec 1, 2025By Bilge Ebiri,Alison Willmore

The Best Movies of 2025

Sprawling dreams of revolution took over the big screen this year, and it’s not hard to imagine why. But subtler forms of catharsis emerged, too. Here are the best movies of 2025.

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Kimora Lee Simmons Is Back on TV: Here’s How to Watch ‘Kimora: Back in the Fab Lane’ Online for Free
WWDDec 1, 2025By Tim Chan

Kimora Lee Simmons Is Back on TV: Here’s How to Watch ‘Kimora: Back in the Fab Lane’ Online for Free

The new E! show follows the model-turned-fashion designer as she navigates new businesses while juggling life as a mom of five kids. Stream it here.

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Annual U.S. healthcare expenditures attributable to cigar smoking between 2001 and 2018, overall and by payer
Plos.orgDec 1, 2025By Xin Xu, Ghada Homsi, Sherry T. Liu, Jennifer M. Gaber, Naa A. Inyang, Brian L. Rostron, Caryn F. Nagler, James Nonnemaker

Annual U.S. healthcare expenditures attributable to cigar smoking between 2001 and 2018, overall and by payer

Background In 2022, 3.7% of U.S. adults currently smoked cigars. This study assesses cigar-smoking-attributable fractions in U.S. healthcare expenditures and associated annual healthcare expenditures overall and by payer, including publicly funded healthcare …

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Genetic determinants of zinc homeostasis and its role in cardiometabolic diseases
Plos.orgDec 1, 2025By Marie C. Sadler, Jean-Pierre Ghobril, Oleg Borisov, Maïwenn Perrais, Guglielmo Schiano, Dusan Petrovic, Eunji Ha, Belén Ponte, Yong Li, Zulema Rodriguez-Hernandez, Menno Pruijm, Daniel Ackermann, Idris Guessous, Silvia Stringhini, Georg Ehret, Tanguy Corre, Bruno Vogt, Pierre-Yves Martin, Halit Ongen, Emmanouil Dermitzakis, Janet E. Williams, Brenda M. Murdoch, Michelle K. McGuire, Courtney L. Meehan, INSPIRE Consortium, Sébastien Lenglet, Katalin Susztak, Julien Vaucher, Aurélien Thomas, Olivier Devuyst, Anna Köttgen, Murielle Bochud, Zoltán Kutalik

Genetic determinants of zinc homeostasis and its role in cardiometabolic diseases

Author summary Zinc is the second most abundant trace element in the human body and plays a key role in processes such as immune function and growth. However, zinc deficiency remains common worldwide, particularly in regions with limited access to nutritious …

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Why the Venezuela-Turkey connection is a ticking time bomb
Israelnationalnews.comDec 1, 2025By Amine Ayoub

Why the Venezuela-Turkey connection is a ticking time bomb

The most dangerous lifeline for the Venezuelan dictatorship today isn't Havana or Moscow. It is Ankara. Opinion.

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Craving More ‘Zootopia’? These Four Dialogue-Free Chinese Shorts Have You Covered
Cartoon BrewDec 1, 2025By Jamie Lang

Craving More ‘Zootopia’? These Four Dialogue-Free Chinese Shorts Have You Covered

Disney and Shanghai Animation Film Studio teamed on this four-pack of 'Zootopia' animated shorts in different traditional Chinese styles.

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Financial PostDec 1, 2025By Bloomberg News

UK Scraps $1 Billion of Support for Total’s Mozambique LNG

The UK government withdrew financing of more than $1 billion for TotalEnergies SE’s liquefied natural gas facility in Mozambique, just as the company looks to resume construction.

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Hurry to Grab These Cyber Monday Tablet Steals: Get Up to 55% Off Apple, Amazon, Samsung, and More
PCMag.comDec 1, 2025By Juhi Wadia

Hurry to Grab These Cyber Monday Tablet Steals: Get Up to 55% Off Apple, Amazon, Samsung, and More

If you want to upgrade your old iPad or gift someone a new tablet this holiday season, you're in luck. We've rounded up 20 top-rated models on sale for Cyber Monday—starting at just $45! Cyber Monday is finally here, and our experts have been working tireless…

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Hurry to Grab These Cyber Monday Tablet Steals: Get Up to 55% Off Apple, Amazon, Samsung, and More
PCMag.comDec 1, 2025By Juhi Wadia

Hurry to Grab These Cyber Monday Tablet Steals: Get Up to 55% Off Apple, Amazon, Samsung, and More

If you want to upgrade your old iPad or gift someone a new tablet this holiday season, you're in luck. We've rounded up 20 top-rated models on sale for Cyber Monday—starting at just $45! Cyber Monday is finally here, and our experts have been working tireless…

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Warren Buffett’s Advice for Getting Rich on an Average Salary
Yahoo EntertainmentDec 1, 2025By Jacob Wade

Warren Buffett’s Advice for Getting Rich on an Average Salary

Learn Warren Buffett’s best advice for building wealth on an average salary and simple strategies to grow your money over time.

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Game on! Grab a rare Cyber Monday PlayStation deal on the PS5 controller
New York PostDec 1, 2025By Miska Salemann

Game on! Grab a rare Cyber Monday PlayStation deal on the PS5 controller

Time to controller your spending.

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Freerepublic.comDec 1, 2025

The Garden Thread - December, 2025

The MONTHLY Gardening Thread is a gathering of folks that love soil, seeds and plants of all kinds. From complete newbies that are looking to start that first potted plant, to gardeners with some acreage, to Master Gardener level and beyond, we would love to …

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Don't Miss Filson's Cyber Monday Sale
esquire.comDec 1, 2025By Tatjana Freund

Don't Miss Filson's Cyber Monday Sale

For Cyber Monday, save 25 percent on Filson's outerwear, flannels, and hoodies. Here, shop our 15 favorite Cyber Monday deals from Filson.

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Slashdot.orgDec 1, 2025By feedfeeder

Another winter storm threatens fresh travel headaches for areas already hit hard over the holiday weekend - CNN

Another winter storm threatens fresh travel headaches for areas already hit hard over the holiday weekendCNN Millions Under Winter Storm Watch as Potential Nor’easter ApproachesThe New York Times Winter Storm Chan Set To Dump Snow, Ice In EastThe Weather Chan…

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Should You Hold Your Stake in Perrigo Company, plc (PRGO)?
Biztoc.comDec 1, 2025By finance.yahoo.com

Should You Hold Your Stake in Perrigo Company, plc (PRGO)?

In its third-quarter 2025 investor letter, Meridian Contrarian Fund highlighted stocks such as Perrigo Company plc (NYSE:PRGO). Perrigo Company plc (NYSE:PRGO) is an over-the-counter health and wellness solutions provider. The one-month return of Perrigo Comp…

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Airline Stocks Are Falling. Thanksgiving Didn’t Go to Plan — the Delays and Cancellations
Biztoc.comDec 1, 2025By barrons.com

Airline Stocks Are Falling. Thanksgiving Didn’t Go to Plan — the Delays and Cancellations

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The best telescopes for astrophotography
Popular ScienceDec 1, 2025By Stacey L. Nash

The best telescopes for astrophotography

Capture the cosmos with a telescope for astrophotography. The post The best telescopes for astrophotography appeared first on Popular Science.

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Giftcards.com Cyber Week Savings Sale: Up to 15% off select gift cards
Dealnews.comDec 1, 2025

Giftcards.com Cyber Week Savings Sale: Up to 15% off select gift cards

Get up to 15% off gift cards during the Giftcards.com Cyber Week Savings Sale. Use promo code "CYBER15" to get 15% off select gift cards or "CYBER10" to get 10% off select gift cards. Shop Now at Giftcards.com

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2025 LEGO Advent Calendar Spoilers: Day 1 [Feature]
Brothers-brick.comDec 1, 2025By Jake Forbes (TBB Managing Editor)

2025 LEGO Advent Calendar Spoilers: Day 1 [Feature]

December is here, and for LEGO fans, that means one thing: time to start opening Advent Calendars! Here at The Brothers Brick, we've been sharing daily reveals since 2015, served with hot mugs of spicy commentary and plates of silly side builds. The spoilers …

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Kffhealthnews.orgDec 1, 2025

Monday, December 1, 2025

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Medical Gases — Current Good Manufacturing Practice
FDA.govDec 1, 2025By FDA

Medical Gases — Current Good Manufacturing Practice

Pharmaceutical Quality/Manufacturing Standards (CGMP)

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WHO gives green-light to Ozempic-style drugs for obesity
ABC News (AU)Dec 1, 2025By Stephanie Dalzell

WHO gives green-light to Ozempic-style drugs for obesity

Ozempic-style medications have been recommended as long-term treatments for obesity under new guidelines released by the World Health Organization.

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Freerepublic.comDec 1, 2025By Cypher News

The Secret ‘Score System’ On X Has Just Been Revealed

Every creator on X is playing a game they were never told the rules to. Your reach isn’t dying by accident. It’s being scored, tiered, and throttled behind your back. If advertisers decide your ideas are “unsafe,” the algorithm buries you before your own foll…

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From porcelain to tweed, EU opens protected label to crafts
Digital JournalDec 1, 2025By AFP

From porcelain to tweed, EU opens protected label to crafts

Traditional crafts from French Limoges porcelain to Irish Donegal tweed became entitled to EU protected status as of Monday — on a par with agricultural products from Champagne to Parma ham. Europe’s glassblowers, potters, jewellers and more will be able to r…

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Trump Vowed to ‘End Inflation’ — His Voters Are Growing Impatient
MediaiteDec 1, 2025By Colby Hall

Trump Vowed to ‘End Inflation’ — His Voters Are Growing Impatient

Trump vowed to make life cheaper fast. Nearly a year later, prices haven’t fallen—they've actually increased — and voters are starting to notice. The post Trump Vowed to ‘End Inflation’ — His Voters Are Growing Impatient first appeared on Mediaite.

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World Health Organization issues first-ever guidelines for use of GLP-1 weight loss medications
ABC NewsDec 1, 2025By Liz Neporent

World Health Organization issues first-ever guidelines for use of GLP-1 weight loss medications

World Health Organization issues first-ever guidelines for use of GLP-1 weight loss medicationsgo.com

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GlobeNewswireDec 1, 2025By Global Times

Global Times- The fading ‘bucket toilets’ highlights Shanghai’s people-centered governance acumen

Shanghai eliminated its old “bucket toilets” after 30 years, greatly improving living conditions and modernizing the city. Shanghai eliminated its old “bucket toilets” after 30 years, greatly improving living conditions and modernizing the city.

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Massive winter weather slams Midwest: Over 1,000 canceled flights amid heavy snow
The Times of IndiaDec 1, 2025By Advaita Suresh

Massive winter weather slams Midwest: Over 1,000 canceled flights amid heavy snow

A severe winter storm swept across the Midwest and Central U.S. during the Thanksgiving weekend, depositing heavy snow and interrupting travel. More than 1,000 flights at Chicago airports were canceled, and major delays impacted O’Hare and Midway. Highways be…

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Have your say: Are you a recent graduate thinking of emigrating?
The Irish TimesDec 1, 2025

Have your say: Are you a recent graduate thinking of emigrating?

Some say it is ‘easier to find work, a place to live and a decent lifestyle’ outside Ireland

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WHO recommends GLP-1 drugs for obesity
NBC NewsDec 1, 2025By Aria Bendix

WHO recommends GLP-1 drugs for obesity

The World Health Organization on Monday recommended GLP-1 drugs as a tool to manage obesity in adults, marking a shift in the way the U.N. agency has historically framed obesity treatment.

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It's official: Global health body makes historic call on weight-loss drugs
New AtlasDec 1, 2025By Bronwyn Thompson

It's official: Global health body makes historic call on weight-loss drugs

The World Health Organization (WHO) has finally made its recommendations on using glucagon-like peptide-1 (GLP-1) therapeutics for weight loss, though it remains to be seen whether it changes their status for prescribing or their price.Continue ReadingCategor…

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iVisa emerges as a travel tech leader: Bootstrapped, borderless, and booming
GlobeNewswireDec 1, 2025By iVisa

iVisa emerges as a travel tech leader: Bootstrapped, borderless, and booming

A conversation with iVisa co-founders David Perez and Sergio Merino on how they are changing how the world travels. A conversation with iVisa co-founders David Perez and Sergio Merino on how they are changing how the world travels.

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Travelers face thousands of flight cancellations and delays in return from Thanksgiving
CBS NewsDec 1, 2025By CBS News

Travelers face thousands of flight cancellations and delays in return from Thanksgiving

Sunday was expected to be the busiest day of the Thanksgiving travel rush, but travelers across the Midwest dealt with a powerful winter storm while trying to return home. Over the weekend, more than 2,900 flights were canceled and 21,000 were delayed.

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Cyber Monday Computer Monitor Deals: Save Big on Top-Rated Brands, Such as Alienware, LG, Samsung, and More
PCMag.comDec 1, 2025By Shubham Yewale

Cyber Monday Computer Monitor Deals: Save Big on Top-Rated Brands, Such as Alienware, LG, Samsung, and More

With Cyber Monday sales dropping left and right, we're seeing over 40% discounts on the best monitors for your gaming, entertainment, or work setup. Cyber Monday monitor deals are now in effect, and prices are dropping rapidly. We're talking deep discounts on…

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When formal systems stop working, neighbors turn to each other in what many call 'mutual aid'
ABC NewsDec 1, 2025By THALIA BEATY Associated Press

When formal systems stop working, neighbors turn to each other in what many call 'mutual aid'

Organizers say that interest in local, grassroots initiatives to meet community needs has been growing

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What is mutual aid? And why are more people turning to informal efforts to help each other?
ABC NewsDec 1, 2025By THALIA BEATY Associated Press

What is mutual aid? And why are more people turning to informal efforts to help each other?

Organizers say that in response to government funding cuts, high prices and political uncertainty, interest in mutual aid efforts has picked up

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Our Two Hotel Horror Stories at Disney World
Disneytouristblog.comDec 1, 2025By Tom Bricker

Our Two Hotel Horror Stories at Disney World

We recently wrapped up a whirlwind family vacation to Walt Disney World for Christmas-time, which included two hotel horror stories. In all honesty, one of them was more amusing than it was awful and the other had a happy ending after a comedy of errors, but …

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West African bloc delegation arrives in Guinea-Bissau for talks with military coup leaders
ABC NewsDec 1, 2025By ASSANA SAMBU Associated Press, MONIKA PRONCZUK Associated Press

West African bloc delegation arrives in Guinea-Bissau for talks with military coup leaders

ECOWAS delegation has arrived in Guinea-Bissau on Monday, as the military government which seized power in the country banned all demonstrations, strikes and activities regarded as threat to peace and stability

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School Closings December 1, 2025: Full list of US districts announcing delays and class cancellations after severe 10-inch snowstorm
The Times of IndiaDec 1, 2025By Aastha Raj

School Closings December 1, 2025: Full list of US districts announcing delays and class cancellations after severe 10-inch snowstorm

School delays: Heavy snowfall, icy secondary roads and alerts over a fast-moving Nor’easter have prompted widespread school closures on December 1, 2025, with major districts across Missouri, Iowa and Michigan issuing Monday schedules that include full cancel…

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Financial PostDec 1, 2025By Bloomberg News

The Best Food and Drink Gifts of the Season

The ultimate gift guide for people who like to cook, bake, eat and drink.

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Financial PostDec 1, 2025By Bloomberg News

Moderna Falls After FDA Vows to Impose New Vaccine Requirements

Moderna Inc. fell in premarket trading Monday after the Food and Drug Administration said in a memo late last week it would place new restrictions on which vaccines hit the market.

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Morrisville-Eaton football coach goes out on top
Utica Observer DispatchDec 1, 2025By Utica Observer-Dispatch

Morrisville-Eaton football coach goes out on top

November 30, 2025, high school football: Morrisville-Eaton defeats Eldred 40-12 in state regional eight-player championship game.

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